THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Changing concentrations of cdk result in binding to cyclin
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Changing concentrations of cyclin result in binding to cdk
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MPF complex formation decreases with increased cdk levels
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MPF complex formation decreases with increased cyclin levels
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Detailed explanation-1: -The formation of cyclin/CDKs controls the cell-cycle progression via phosphorylation of the target genes, such as tumor suppressor protein retinoblastoma (Rb). The activation of cyclins/CDKs is induced by mitogenic signals and inhibited by the activation of cell-cycle checkpoints in response to DNA damage [8].
Detailed explanation-2: -Cyclins drive the events of the cell cycle by partnering with a family of enzymes called the cyclin-dependent kinases (Cdks). A lone Cdk is inactive, but the binding of a cyclin activates it, making it a functional enzyme and allowing it to modify target proteins.
Detailed explanation-3: -describe the changes in the concentration of cyclin as the cell moves through different phases of the cell cycle. the concentration of cyclin is minimal at the start of G1 but increases until almost through mitosis, and quickly drops to a minimal level once again.