AP BIOLOGY

Detailed explanation-1: -In long-distance endocrine signaling, signals are produced by specialized cells and released into the bloodstream, which carries them to target cells in distant parts of the body. Signals that are produced in one part of the body and travel through the circulation to reach far-away targets are known as hormones.

Detailed explanation-2: -Long distance signaling is a type of cell communication whereby the signaling molecules act on a target cell that is far from the signaling cell. On the other hand, local signaling is when cells that are close to one another communicate using signals such as paracrine signals.

Detailed explanation-3: -Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to cell signaling by endocrine factors, hormones which travel considerably longer distances via the circulatory system; juxtacrine interactions; and autocrine signaling.

Detailed explanation-4: -Autocrines are long-distance chemical signals that travel in blood throughout the body.