THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Conformational Change of Receptor
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Transcription Factor
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Phosphorylation Cascade
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Release of Ca2+ from Smooth ER
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Detailed explanation-1: -The transcription factors Oct4, Sox2, Klf4 and Nanog act as triggers for the induction of somatic cells to pluripotent stem cells. Oct4, Sox2, Klf4 and Nanog are all essential in stem cells and play an important role in biological processes.
Detailed explanation-2: -Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that initiate and regulate the transcription of genes.
Detailed explanation-3: -Common examples of general transcription factors include TFIIA and TFIIB.
Detailed explanation-4: -Many transcription factors are either tumor suppressors or oncogenes, and, thus, mutations or aberrant regulation of them is associated with cancer. Three groups of transcription factors are known to be important in human cancer: (1) the NF-kappaB and AP-1 families, (2) the STAT family and (3) the steroid receptors.