AP BIOLOGY

Detailed explanation-1: -Gap junctions are clusters of intercellular channels facilitating a direct connection between the cytoplasm of two neighbouring cells to mediate intercellular communication. These channels are formed by channel-forming proteins that are densely packed into spatial microdomains of the plasma membrane.

Detailed explanation-2: -Gap junctions are specialized intercellular connections between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulated gate between cells.

Detailed explanation-3: -Paracrine signaling Often, cells that are near one another communicate through the release of chemical messengers (ligands that can diffuse through the space between the cells). This type of signaling, in which cells communicate over relatively short distances, is known as paracrine signaling.

Detailed explanation-4: -A space located or occurring between cells is often referred to as an intercellular space. When the space is passing a cell, or cell membrane or situated beside or between cells the term paracellular space is usually used.