THE CELL
CELL COMMUNICATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
The binding of a ligand to a receptor molecule causes the receptor to change shape
|
|
|
All ligands are proteins
|
|
|
Each ligand is only able to bind to one specific receptor
|
|
|
Ligands can bind to cell-surface receptors, but they cannot enter the cell
|
Detailed explanation-1: -When a ligand binds to a cell-surface receptor, the receptor’s intracellular domain (part inside the cell) changes in some way. Generally, it takes on a new shape, which may make it active as an enzyme or let it bind other molecules. The change in the receptor sets off a series of signaling events.
Detailed explanation-2: -When a ligand binds an ion channel receptor, a channel through the plasma membrane opens that allows specific ions to pass through. This process requires a specialized membrane-spanning region of the receptor.
Detailed explanation-3: -Ligand binding to a receptor protein alters the conformation by affecting the three-dimensional shape orientation. The conformation of a receptor protein composes the functional state. Ligands include substrates, inhibitors, activators, signaling lipids, and neurotransmitters.
Detailed explanation-4: -When a ligand (the paracrine factor) binds its receptor in the extracellular region, the ligand induces a conformational change in the receptor’s structure. This shape change is transmitted through the membrane and changes the shape of the cytoplasmic domains.