THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The growth factor binds to cells in the same area and holds them together to form a multicellular structure
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The growth factor binds to a receptor on the cell membrane, initiating a signal transduction pathway that results in a change in gene expression
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The growth factor binds to sugar molecules in the extracellular space and provides them as an energy source
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The growth factor binds to phospholipids in the cell membrane, creating a channel through which substances enter the cell
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Detailed explanation-1: -In animals, by contrast, cell growth and cell division both depend on signals from other cells. The extracellular growth factors that stimulate cell growth bind to receptors on the cell surface and activate intracellular signaling pathways.
Detailed explanation-2: -Growth factors (GFs) are a group of proteins stimulating the growth of specific tissues. GF plays important roles in the regulation of cell division that drives cell proliferation. Each GF binds to a specific cell–surface receptor.
Detailed explanation-3: -Cell cycle progression is mediated by cyclin-dependent kinases (Cdks) and their regulatory cyclin subunits. However, the driving force of cell cycle progression is growth factor-initiated signaling pathways that control the activity of various Cdk-cyclin complexes.
Detailed explanation-4: -The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast cancer.