THE CELL
STRUCTURE AND FUNCTION OF THE CELL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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They would have difficulty producing proper volumes of urine.
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They would produce too much dilute urine.
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They would become dehydrated more easily.
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Their blood pressure would decrease.
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Detailed explanation-1: -Most of the known AQP2 gene mutations cause the aquaporin 2 protein to be misfolded into an incorrect 3-dimensional shape. The misfolded protein is trapped within the cell, where it is unable to reach the cell membrane to transport water molecules.
Detailed explanation-2: -When plant aquaporins are silenced, the hydraulic conductance and photosynthesis of the leaf decrease. When gating of plant aquaporins occurs, it stops the flow of water through the pore of the protein.
Detailed explanation-3: -Pathophysiology of Aquaporins Malfunction or mutations in AQP2 or, more commonly the V2R, cause nephrogenic diabetes insipidus (NDI), in which patients are unable to concentrate their urine and theoretically could void up to 18 L of dilute urine each day, that is, the amount normally reabsorbed in the collecting duct.
Detailed explanation-4: -Aquaporins are channel proteins that facilitate the transport of water across the cell membrane. One group of researchers hypothesizes that without functional aquaporins, no water will be able to enter the cell.