AP BIOLOGY

Detailed explanation-1: -The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins. Sometimes, when those proteins are made improperly, the proteins stay within the endoplasmic reticulum.

Detailed explanation-2: -ROUGH ENDOPLASMIC RETICULUM These are called membrane bound ribosomes and are firmly attached to the outer cytosolic side of the ER About 13 million ribosomes are present on the RER in the average liver cell. Rough ER is found throughout the cell but the density is higher near the nucleus and the Golgi apparatus.

Detailed explanation-3: -Ribophorin, also known as a ribosome receptor protein, is a transmembrane glycoprotein that aids in the binding of ribosomes to the endoplasmic reticulum’s outer surface, generating rough endoplasmic reticulum. They attach the ribosome’s larger subunit (the 50S) to the rough endoplasmic reticulum.

Detailed explanation-4: -The ribosomes attached to the ER are being used to make proteins that are inserted into the membrane, proteins that are to be secreted out of the cell, and proteins that are found in various membrane bound organelles like the Golgi. Ribosomes floating freely synthesize all the other proteins.