THE HUMAN IMMUNE SYSTEM
AIDS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Reduction of T-lymphocyte level
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Decrease in B-lymphocyte level
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Reduction in the level of natural killers (NK cells)
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Decrease in the level of the system of the complement
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Insufficiency of effector cells of humoral immunity
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Detailed explanation-1: -One of the most common signs of primary immunodeficiency is having infections that are more frequent, longer lasting or harder to treat than are the infections of someone with a typical immune system. You may also get infections that a person with a healthy immune system likely wouldn’t get (opportunistic infections).
Detailed explanation-2: -Begin testing with complete blood count (with manual differential), quantitative immunoglobulin levels, antibody titers, and skin testing for delayed hypersensitivity. Select additional tests based on what type of immune defect is suspected (humoral, cellular, phagocytic cell, or complement).
Detailed explanation-3: -Background. Adenosine deaminase (ADA) is a key enzyme of the purine salvage pathways and deficiency caused by mutations in the ADA gene results in one of the more common causes of autosomal recessive severe combined immunodeficiency (SCID), accounting for approximately 10–15% of cases in outbred populations [1].
Detailed explanation-4: -The secondary antibody response is characterized in its first few days by the production of small amounts of IgM antibody and larger amounts of IgG antibody, with some IgA and IgE.