AP BIOLOGY

Detailed explanation-1: -Anabolic steroids can potentially cause a multitude of negative effects on the liver. These may include transient elevations of transaminases, acute cholestatic syndrome, chronic vascular injury to the liver (peliosis hepatis), benign adenoma and hepatocellular carcinoma, or TAFLD.

Detailed explanation-2: -Aggression. Case reports and small studies indicate that anabolic steroids increase irritability and aggression, 75 although findings may be confounded by personality traits that are overrepresented in steroid users (i.e., antisocial, borderline, and histrionic personality disorder)78 and use of other drugs.

Detailed explanation-3: -Steroid misuse can cause acne, 70–72 hair loss on the head, cysts, and oily hair and skin. Users who inject steroids may also develop pain and abscess formation at injection sites. Anabolic steroids can also produce jaundice, or yellowing of the skin or eyes, as a result of damage to the liver.

Detailed explanation-4: -The liver injury generally arises within 1 to 4 months of starting therapy, but may be delayed to as long as 6 to 24 months (Case 1). The onset is usually insidious with development of nausea, fatigue and itching followed by dark urine and jaundice.