AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

BLOOD GROUPS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Someone with type O blood donates plasma to someone with type A blood. What happens?
A
The transfusion goes well with no negative results.
B
Agglutination occurs in the person with type A blood. This affects the donor cells.
C
Agglutination occurs in the person with type A blood. This affects their own cells.
D
Agglutination occurs in the person with type O blood because they have Anti-A antibodies.
Explanation: 

Detailed explanation-1: -Anti-B attacks red cells of Group B or AB. If ABO incompatible red cells are transfused, red cell haemolysis can occur. For example if group A red cells are infused into a recipient who is group O, the recipient’s anti-A antibodies bind to the transfused cells.

Detailed explanation-2: -For example, a sample of type A blood will clump when tested with type B antibodies as it contains type A antigens. Whereas, a type O blood sample will not agglutinate with either type A or type B antibodies as type O blood contains no antigens.

Detailed explanation-3: -A person with O blood who received a transfusion from a type A donor would experience agglutination because type O blood contains Anti-A antibodies which agglutinates with A antigens present in the type A blood.

Detailed explanation-4: -Acute immune hemolytic reaction It happens when donor and patient blood types do not match. The patient’s antibodies attack the transfused red blood cells, causing them to break open (hemolyze) and release harmful substances into the bloodstream.

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