AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

BLOOD GROUPS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following statements is true when Kx protein is absent?
A
Kell antigens will be increased
B
Kell antigens will not be expressed
C
Kx antigen will be expressed
D
006.001 will be expressed
Explanation: 

Detailed explanation-1: -On RBCs the Kell glycoprotein is covalently linked to the XK protein. The absence of XK protein leads to the McLeod syndrome that is characterized by mild hemolysis, late onset forms of muscular and neurological defects, red cell acanthocytosis, and a greatly reduced amount of the Kell protein [76].

Detailed explanation-2: -An antigen is any substance to which the immune system can respond. For example, components of the bacterial cell wall can trigger severe and immediate attacks by neutrophils. If the immune system encounters an antigen that is not found on the body’s own cells, it will launch an attack against that antigen.

Detailed explanation-3: -The Kell antigen system (also known as the Kell–Cellano system) is a human blood group system, that is, a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells.

Detailed explanation-4: -The most common causes of isoimmunization are blood transfusion, and fetal-maternal hemorrhage.

There is 1 question to complete.