THE HUMAN IMMUNE SYSTEM
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Months to Years
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Weeks to Months
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Less than 72 hours
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5-10 Days
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Detailed explanation-1: -IgM and IgG antibodies Typically the IgM antibody develops soon after infection (3 to 10 days), but does not last long. The IgG is often detectable later, after day 9, and can last much longer, months to years.
Detailed explanation-2: -Uses. Normal immunoglobulin (containing 10%–18% protein) is administered by intramuscular injection for the protection of susceptible contacts against hepatitis A virus (infectious hepatitis), measles and, to a lesser extent, rubella. Injection of immunoglobulin produces immediate protection lasting several weeks.
Detailed explanation-3: -For total IgG, the half-life found was 25.8 days; for IgG1 it was 29.7 days; for IgG2 it was 26.9 days; and for IgG3 it was 15.7 days. The results are similar to those reported for endogeneous IgG.
Detailed explanation-4: -Monoclonal antibodies, specifically those of the IgG class, experience significantly longer half-lives than other molecules. Additionally, IgGs have a high degree of target specificity.