THE HUMAN IMMUNE SYSTEM
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IL-1
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IL-3
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IL-4
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IL-6
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Detailed explanation-1: -The release of cytokines is centrally important to many aspects of T cell function. IL-1 is involved in T cell activation. IL-2 is a potent T cell growth factor which is essential for the long-term proliferation of activated T cells.
Detailed explanation-2: -IL-2 is essential for thymic Treg development and regulates Treg homeostasis and suppressive function. Analogous to activated conventional T lymphocytes, IL-2R signaling also plays an important part in Treg cell growth, survival, and effector differentiation.
Detailed explanation-3: -IL-2 was first described as a growth and survival factor capable of inducing T cell proliferation, and the elimination of IL-2 from proliferating T cells can lead to cytokine withdrawal-mediated cell death. However, IL-2 has since been shown to also have negative regulatory effects on T cell responses.
Detailed explanation-4: -Interleukin-2 is made by a type of T lymphocyte. It increases the growth and activity of other T lymphocytes and B lymphocytes, and affects the development of the immune system.