THE HUMAN IMMUNE SYSTEM
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Epitope
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T-helper cell
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Antigen-presenting cell
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MHC-I
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Detailed explanation-1: -Antibody specificity can be assessed by comparing binding signals in cells expressing the target protein to control cells with the target gene knocked out by CRISPR or RNA interference (RNAi). A highly specific antibody should show no binding activity if the target isn’t there.
Detailed explanation-2: -The heavy chain constant regions determine which antibody class the antibody belongs to. The various antibody classes are found in different compartments of the body. For example, IgA is present in the saliva while IgG and IgM are found in the blood.
Detailed explanation-3: -An antigenic determinant is the site of an antigen molecule that is termed an epitope and interacts with the specific antigen-binding site in the variable region of an antibody molecule known as a paratope.