THE HUMAN IMMUNE SYSTEM
IMMUNE RESPONSE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Does not acquire immune memory after initial exposure to antigen
|
|
|
Amplify inflammatory response after bacterial infection
|
|
|
Possess CD16, CD56 and CD3 surface proteins
|
|
|
Major early role in recognizing and killing virus-infected host cells and tumor cells
|
Detailed explanation-1: -The Fc receptor CD16 is present on essentially all CD56dim peripheral blood natural killer (NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells, which eliminate targets through direct killing and cytokine production.
Detailed explanation-2: -CD56 is the archetypal phenotypic marker of natural killer cells but can actually be expressed by many more immune cells, including alpha beta T cells, gamma delta T cells, dendritic cells, and monocytes.
Detailed explanation-3: -CD3-CD16+CD56+ are cytotoxic lymphoctyes also known as Natural Killer (NK) cells. NK lymphocytes destroy cells that are infected by viruses, cancer cells, or cells that are subject to rejection after tissue transplantation.
Detailed explanation-4: -Natural killer (NK) cells are large granular lymphocytes capable of killing tumour cells in a non-MHC restricted manner. NK cells do not express cell-surface CD3, or any known target recognition structure analogous to the T cell antigen receptor (TCR) heterodimers (alpha beta or gamma delta).