AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why must donated tissue be analyzed before it is transplanted into another person?
A
to prevent the recipient’s body from attacking and rejecting the tissue as foreign
B
to eliminate the introduction of pathogens into the recipient
C
to prevent the recipient’s red blood cells from clotting
D
to prevent the formation of antigens in the donated tissue
Explanation: 

Detailed explanation-1: -This is because the person’s immune system detects that the antigens on the cells of the organ are different or not “matched.” Mismatched organs, or organs that are not matched closely enough, can trigger a blood transfusion reaction or transplant rejection .

Detailed explanation-2: -Tissue typing ensures that an organ from a donor will be compatible with its recipient. The process starts with identifying the unique human leukocyte antigens (HLAs) for the organ donor and recipient, either from blood or tissue.

Detailed explanation-3: -Graft rejection occurs when the recipient’s immune system attacks the donated graft and begins destroying the transplanted tissue or organ. The immune response is usually triggered by the presence of the donor’s own unique set of HLA proteins, which the recipient’s immune system will identify as foreign.

Detailed explanation-4: -Types of Organ Rejection Acute rejection happens when your body’s immune system treats the new organ like a foreign object and attacks it. We treat this by reducing your immune system’s response with medication. Chronic rejection can become a long-term problem. Complex conditions can make rejection difficult to treat.

Detailed explanation-5: -Medications After a Transplant. After an organ transplant, you will need to take immunosuppressant (anti-rejection) drugs. These drugs help prevent your immune system from attacking ("rejecting") the donor organ. Typically, they must be taken for the lifetime of your transplanted organ.

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