AP BIOLOGY

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THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A transfusion reaction with clinical symptoms in the form of fever, but not followed by a hemolytic reaction of red blood cells but rather occurs due to the release of cytokines from leukocyte cells is called
A
Fanhatra
B
THRILLS
C
PTP
D
TA-GVHD
E
Anaphylactic Reaction
Explanation: 

Detailed explanation-1: -Classically, acute hemolytic transfusion reaction is described as a triad of symptoms; fever, flank pain, and red or brown urine. However, this classic presentation is not seen often. Other symptoms are chills, hypotension, renal failure, back pain, or signs of disseminated intravascular coagulation.

Detailed explanation-2: -Cause: Fever and chills during transfusion are thought to be caused by recipient antibodies reacting with white cell antigens or white cell fragments in the blood product or due to cytokines which accumulate in the blood product during storage.

Detailed explanation-3: -Developing a fever after a transfusion is not serious. A fever is your body’s response to the white blood cells in the transfused blood. However, it can be a sign of a serious reaction if the patient is also experiencing nausea or chest pain.

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