THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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CD3
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CD5
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CD10
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CD20
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Detailed explanation-1: -In B-lineage ALL the most important markers for diagnosis, differential diagnosis and subclassification are CD19, CD20, CD22, CD24, and CD79a. The earliest B-lineage markers are CD19, CD22 (membrane and cytoplasm) and CD79a.
Detailed explanation-2: -(pree-KER-ser B-LIM-foh-BLAS-tik loo-KEE-mee-uh) An aggressive (fast-growing) type of leukemia (blood cancer) in which too many B-cell lymphoblasts (immature white blood cells) are found in the bone marrow and blood. It is the most common type of acute lymphoblastic leukemia (ALL).
Detailed explanation-3: -According to the French-American-British (FAB) classification, acute lymphoblastic leukemia may be classified into 3 subgroups: ALL-L1 (small uniform cells), ALL-L2 (large varied cells) and ALL-L3 (large varied cells with vacuoles).
Detailed explanation-4: -Acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) is a clonal hematopoietic stem cell disorder of B or T cell origin. The World Health Organization (WHO) 2017 classification system categorizes these disease entities under precursor lymphoid neoplasm.