AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Non-regenerative anemia, which of the following is the most common cause in dogs and cats?
A
Anemia of renal disease
B
Iron deficiency anemia
C
Myelophthisis
D
Anemia of inflammatory (chronic) disease
Explanation: 

Detailed explanation-1: -Longterm kidney disease is a common cause of nonregenerative anemia in animals. Animals with kidney disease produce less of a kidney hormone called erythropoietin that stimulates development of red blood cells in the bone marrow, leading to anemia. A synthetic form of the hormone has been used for treatment.

Detailed explanation-2: -Common causes of aplastic or non-regenerative anemia in dogs include bone marrow disease, kidney disease, exposure to toxins, parvovirus, chemotherapy drugs and other medications.

Detailed explanation-3: -Anemia of Inflammatory Disease (AID) is the most common nonregenerative anemia in dogs and cats. It’s typically a mild to moderate normocytic normochromic anemia that can be caused by inflammatory, infectious (bacterial, viral, fungal, protozoal), neoplastic, toxic or immune-mediated disorders.

Detailed explanation-4: -When a cat has non-regenerative anemia, the bone marrow is unable to adequately respond to the decreased number of red blood cells. Non-regenerative anemia in cats is most often caused by kidney failure (renal failure). If your cat is healthy their kidneys create a hormone that helps to produce red blood cells.

Detailed explanation-5: -Non-regenerative anemia is a deficiency of the red blood cells where the bone marrow is not appropriately addressing the deficiency by increasing red blood cell production and releasing reticulocytes. Symptoms include lethargy, jaundice, fever, pale mucous membranes, and abnormal pulses. Protect yourself and your pet.

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