AP BIOLOGY

Detailed explanation-1: -The 30-minute rule states that red blood cell (RBC) units left out of controlled temperature storage for more than 30 minutes should not be returned to storage for reissue; the 4-hour rule states that transfusion of RBC units should be completed within 4 hours of their removal from controlled temperature storage.

Detailed explanation-2: -All blood products taken from the blood bank must be hung within 30 minutes and administered (infused) within 4 hours due to the risk of bacterial proliferation in the blood component at room temperature.

Detailed explanation-3: -Blood components must be transfused within 4 hours of issue. If the transfusion is interrupted for any reason, administration must be discontinued after 4 hours even if the transfusion is not complete.

Detailed explanation-4: -Transfusions must be completed within 4 hours of removal from controlled temperature storage. Many patients can be safely transfused over 90–120 minutes per unit.

Detailed explanation-5: -According to the American Cancer Society, each unit of red blood cells takes around 2 hours to transfuse.