AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The type of Ab in the red blood group system that is more likely to cause an acute hemolytic immune reaction is EXCEPT ____
A
you a
B
Anti Kell
C
you are jk
D
you are in
E
you d
Explanation: 

Detailed explanation-1: -Antibodies against Rh (CEce) and Kidd (Jka and Jkb) system antigens are mostly implicated in delayed hemolytic transfusion reactions (DHTR), which is a potentially life-threatening complication observed in patients receiving chronic transfusions.

Detailed explanation-2: -Acute hemolytic transfusion reactions are usually caused by ABO incompatibility. This potentially fatal complication occurs in about 1 in 30, 000 transfusions. As little as 20 to 30 mL of incompatible RBCs can cause agitation, nausea and vomiting, dyspnea, fever, flushing, hypotension, tachycardia, and hemoglobinuria.

Detailed explanation-3: -Classically, acute hemolytic transfusion reaction is described as a triad of symptoms; fever, flank pain, and red or brown urine. However, this classic presentation is not seen often. Other symptoms are chills, hypotension, renal failure, back pain, or signs of disseminated intravascular coagulation.

There is 1 question to complete.