THE HUMAN IMMUNE SYSTEM
TRANSFUSION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
the most common involvement is glomerular
|
|
|
the most frequent lesion is tubular
|
|
|
velcade can worsen kidney damage
|
|
|
hypercalcemia can worsen kidney damage
|
Detailed explanation-1: -Although hypercalcemia is a known metabolic complication of sarcoidosis, it is rarely a presenting manifestation. Long-standing hypercalcemia and hypercalciuria can cause nephrocalcinosis and chronic renal failure. Acute renal failure, although described, is also a rare presentation of patients with sarcoidosis.
Detailed explanation-2: -In myeloma, as the plasma cells grow uncontrollably, they can produce extremely large amounts of antibody. The antibody passes in to the blood, and can cause problems with the kidneys. Damage occurs if the antibody passes through the filters in the kidneys into tiny drainage tubes.
Detailed explanation-3: -Severe hypercalcemia can damage your kidneys, limiting their ability to cleanse the blood and eliminate fluid. Nervous system problems. Severe hypercalcemia can lead to confusion, dementia and coma, which can be fatal.
Detailed explanation-4: -Renal failure is a frequent complication in patients with multiple myeloma (MM) that causes significant morbidity. In the majority of cases, renal impairment is caused by the accumulation and precipitation of light chains, which form casts in the distal tubules, resulting in renal obstruction.