THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the midostaurin
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le Mylotarg
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Inotuzumab
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Le brentuximab
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Obinutuzumab
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Detailed explanation-1: -Antibody drug conjugates work like a “smart bomb” directed against cancer cells. These drugs are composed of 3 parts: an antibody drug that is specific for the type of cancer being targeted, a cytotoxic chemotherapy drug, and a linker protein to hold the 2 parts together.
Detailed explanation-2: -Brentuximab vedotin contains a monoclonal antibody that binds to a protein called CD30, which is found on some lymphoma cells. It also contains an anticancer drug, which may help kill cancer cells. Brentuximab vedotin is a type of antibody-drug conjugate. Also called Adcetris and SGN-35.
Detailed explanation-3: -Antibody generation and mechanisms of action Brentuximab vedotin binds to the CD30 receptor and is internalized via endocytosis. Upon exposure to proteolytic lysosomal enzymes, MMAE molecules are released in the intracellular space.