AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What can allergic transfusion accidents be due to?
A
to a donor IgG/anti-recipient IgG conflict
B
to a donor IgA/anti-recipient IgA conflict
C
to a donor IgE/anti-recipient IgE conflict
D
LBP preservation product
Explanation: 

Detailed explanation-1: -According to a 2012 article, septic transfusion reactions typically occur due to bacterial contamination of the donor blood components, most commonly from the platelet products. The bacteria in platelets that can cause a septic transfusion reaction include Staphylococcus aureus and Staphylococcus epidermidis.

Detailed explanation-2: -Definition. Transfusion reactions include urticaria, fevers, and hemolysis caused by antibodies in the recipient directed against components of the transfused product, including antigens on the red blood cells (RBCs) themselves, plasma proteins, or antigens on contaminating white blood cells or platelets.

Detailed explanation-3: -Today, the leading causes of allogeneic blood transfusion (ABT)–related mortality in the United States-in the order of reported number of deaths-are transfusion-related acute lung injury (TRALI), ABO and non-ABO hemolytic transfusion reactions (HTRs), and transfusion-associated sepsis (TAS).

Detailed explanation-4: -The most common immediate adverse reactions to transfusion are fever, chills and urticaria.

There is 1 question to complete.