AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the shelf life of transfused platelets
A
7 days
B
1 to 2 days
C
3 to 4 days
D
10 to 12 days
Explanation: 

Detailed explanation-1: -All platelets are stored at room temperature (20-24ºC) with gentle agitation until issue. The shelf life is 5 days from the date of collection.

Detailed explanation-2: -Transfused platelets have an expected life-span of 3-4 days. This may be significantly reduced due to immune refractoriness, consumption, or sequestration. Common causes of suboptimal platelet count increments include ongoing bleeding, DIC, sepsis, fever, and hypersplenism.

Detailed explanation-3: -Platelets (PLTs) are usually stored for up to 5 days prior to transfusion, although in some blood services the storage period is extended to 7 days. During storage, changes occur in both PLT and storage medium, which may lead to PLT activation and dysfunction.

Detailed explanation-4: -To ensure the efficacy of transfused PLTs, they must be stored at room temperature. Due to this storage requirement, PLTs have a short shelf life compared with other blood components of up to 5–7 days to minimize the risk of bacterial contamination.

Detailed explanation-5: -Red cells are stored in refrigerators at 6ºC for up to 42 days. Platelets are stored at room temperature in agitators for up to five days.

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