AP BIOLOGY

Detailed explanation-1: -Heinz bodies are indicative of oxidative injury to the erythrocyte. They are clumps of irreversibly denatured hemoglobin attached to the erythrocyte cell membrane.

Detailed explanation-2: -Heinz body anemia is a type of hemolytic anemia, which happens when your red blood cells break down faster than your body can replace them.

Detailed explanation-3: -Causes. Heinz bodies are formed by damage to the hemoglobin component molecules, usually through oxidative damage by administered drugs, or from an inherited mutation (i.e. change of an internal amino acid residue).

Detailed explanation-4: -Heinz bodies stain the same red-pink color of mature RBCs with routine Wright stains, and stain pale basophilic with Diff-Quik stain. With Diff-Quik stain, Heinz bodies may be seen both as round projections from the RBC membrane and as clear round inclusions that have not yet projected out from the RBC membrane.