AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is an indispensable mainstay therapy in IMHA?
A
Corticosteroid
B
Azathioprine
C
Cyclosporin
D
Mycophenolate mofetil
Explanation: 

Detailed explanation-1: -IMHA is treated with immunosuppressive medications, anti-thrombotic medications, and supportive therapy including blood transfusions. Multiple blood transfusions are often needed to stabilize the patient while waiting for immunosuppressive medications to take effect.

Detailed explanation-2: -Blood transfusions Most dogs with IMHA require at least one blood transfusion, and many require two or more. Each blood transfusion must be appropriate for your dog’s blood type and carefully administered over 4 hours to prevent transfusion reactions.

Detailed explanation-3: -It had been shown that corticosteroids depress the rate of hemolysis or diminish the titer of antibody, thus enabling the overly active erythropoiesis to reach a satisfactory equilibrium with the peripheral red blood cell count.

Detailed explanation-4: -The traditional treatment of AIHA includes corticosteroids, splenectomy and conventional immunosuppressive drugs. Over recent years, some new therapies have become available and there has been some evidence of success.

There is 1 question to complete.