AP BIOLOGY

THE HUMAN IMMUNE SYSTEM

TRANSFUSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is sickle-cell anemia harmful?
A
it programs WBCs to attack self cells
B
it hinders the ability to carry oxygen
C
it decreases resistance against malaria
D
it isn’t harmful
Explanation: 

Detailed explanation-1: -When they lose their oxygen, they form into the shape of a sickle or crescent, like the letter C. These cells stick together and can’t easily move through the blood vessels. This can block small blood vessels and the movement of healthy, normal oxygen-carrying blood.

Detailed explanation-2: -Blood of patients with sickle cell anemia (SS) exhibits decreased affinity for oxygen, although the oxygen affinity of hemoglobin S is the same as that of hemoglobin A. SS red cells contain more 2, 3-diphosphoglycerate (DPG) than normal erythrocytes.

Detailed explanation-3: -These cells do not bend or move easily and can block blood flow to the rest of your body. The blocked blood flow through the body can lead to serious problems, including stroke, eye problems, infections, and episodes of pain called pain crises. Sickle cell disease is a lifelong illness.

Detailed explanation-4: -Oxygen therapy may prevent the vaso-occlusion and disruption of tissue oxygenation that often lead to painful sickle cell disease crises.

There is 1 question to complete.