THE HUMAN IMMUNE SYSTEM
TRANSFUSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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YOUR patient has a collapse 3 hours after the transfusion of 2 CGR? What diagnoses do you suspect and what samples should be taken urgently?
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a TRALI
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bacterial shock
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hemolytic shock
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anti-HLA/typage HLA
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IgA
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Explanation:
Detailed explanation-1: -Severe anaphylactic or allergic reactions may occur during blood transfusion to patients who are IgA-deficient and have anti-IgA in their blood, particularly those with class-specific antibodies.
Detailed explanation-2: -From a transfusion medicine perspective, the presence of anti-IgA in an IgA deficient recipient is a possible cause of anaphylactic transfusion reactions.
Detailed explanation-3: -Laboratory Investigation. When a transfusion reaction is suspected it has to be reported using the ‘Report of a Suspected Adverse Transfusion Reaction/Event’ form WRH-BT-HF-006. Procedure for Blood Culturing of implicated Red Cell Pack/ Blood component.
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