AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A base pair substitution is the:
A
addition or deletion of a nitrogen base.
B
replacement of one nitrogen base with another.
C
none of the above.
Explanation: 

Detailed explanation-1: -noun, plural: base pair substitutions. A type of mutation involving replacement or substitution of a single nucleotide base with another in DNA or RNA molecule. Supplement. This type of mutation occurring in noncoding sequences often does not result in an altered amino acid sequence during translation.

Detailed explanation-2: -Base Substitutions Single base substitutions are called point mutations, recall the point mutation Glu—–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

Detailed explanation-3: -Missense: A missense variant is a type of substitution in which the nucleotide change results in the replacement of one protein building block (amino acid) with another in the protein made from the gene.

Detailed explanation-4: -Base substitutions of one nitrogenous base in DNA cause point mutation.

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