AP BIOLOGY

Detailed explanation-1: -A mutation is a change in a genetic sequence. Mutations include changes as small as the substitution of a single DNA building block, or nucleotide base, with another nucleotide base. Meanwhile, larger mutations can affect many genes on a chromosome.

Detailed explanation-2: -There are three types of DNA Mutations: base substitutions, deletions and insertions. Single base substitutions are called point mutations, recall the point mutation Glu—–> Val which causes sickle-cell disease.

Detailed explanation-3: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.