AP BIOLOGY

Detailed explanation-1: -A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism’s genome.

Detailed explanation-2: -Substitution, as related to genomics, is a type of mutation in which one nucleotide is replaced by a different nucleotide. The term can also refer to the replacement of one amino acid in a protein with a different amino acid.

Detailed explanation-3: -… A point mutation occurs in a genome when a single base pair is added, deleted or changed. While most point mutations are benign, they can also have various functional consequences, including changes in gene expression or alterations in encoded proteins.

Detailed explanation-4: -A genetic alteration caused by the substitution of a single nucleotide for another nucleotide. Also called point variant.

Detailed explanation-5: -In general, a mutation is when a gene is altered through a change in DNA structure; this may refer even to entire sections of chromosomes. A point mutation is specifically when only one nucleotide base is changed in some way, although multiple point mutations can occur in one strand of DNA or RNA.