AP BIOLOGY

Detailed explanation-1: -Contact inhibition enables noncancerous cells to cease proliferation and growth when they contact each other. This characteristic is lost when cells undergo malignant transformation, leading to uncontrolled proliferation and solid tumor formation.

Detailed explanation-2: -Cancer cells do not respond to the signals and safeguards that are in place. Because cancer cells don’t respond appropriately, they grow uncontrollably and can eventually damage the tissues around them. If cancer cells continue to grow, they will eventually form a mass called a tumor.

Detailed explanation-3: -Cancer cells are often very sensitive to growth factors. So if we can block them, we can stop some types of cancer from growing and dividing. Scientists are developing different inhibitors for the different types of growth factors.

Detailed explanation-4: -noun. : cessation of cellular movement, growth, and division upon contact with other cells.

Detailed explanation-5: -Contact inhibition arrests the cell growth when cells come in contact with each other. So, the normal cells stop proliferating. Contact inhibition is lost in cancer cells. Cancer cells do not arrest their growth but it continues to proliferate and piles up on the top of each other forming a multilayered foci.