THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the relative proportion of each of the four bases differs within individuals of a species
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the human genome is more complex than that of other species
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The amount of A is always equivalent to T, and C to G
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the amount of ribose is always equivalent to deoxyribose
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Detailed explanation-1: -Rule 2. In 1947 Chargaff showed that the composition of DNA, in terms of the relative amounts of the A, C, G and T bases, varied from one species to another. This molecular diversity added evidence that DNA could be the genetic material.
Detailed explanation-2: -Chargaff’s rules are important because they point to a kind of “grammar of biology”, a set of hidden rules that govern the structure of DNA. This grammar ought to reveal itself as patterns in DNA that are invariant across all species.
Detailed explanation-3: -According to Chargaff’s rules, the percentages of adenine are equal to those of thymine and the percentages of cytosine are equal to those of guanine in the DNA molecule. The nitrogen bases are held together in the center of the molecule by Hydrogen Bonds.
Detailed explanation-4: -Erwin Chargaff (Czernowitz, August 11, 1905 – New York City, USA, June 20, 2002) was an Austrian biochemist who emigrated to the United States during the Nazi era. Through careful experimentation, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA.