AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Chargraff’s base pairing rules state that because a pyramidine ( ____ ring) pairs with a purine ( ____ ring), the helix has uniform width. Fill in the blanks.
A
single, double
B
double, single
C
single, single
D
double, double
Explanation: 

Detailed explanation-1: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.

Detailed explanation-2: -Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule.

Detailed explanation-3: -Chargaff found that double-stranded DNA contains approximately a 1:1 ratio of adenine and thymine, and approximately a 1:1 ratio of cytosine and guanine.

There is 1 question to complete.