AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
During semiconservative replication, the DNA sequence ACT results in which sequence on the new strand?
A
ACT
B
TCA
C
TGA
D
UGA
Explanation: 

Detailed explanation-1: -Each new strand formed will be identical to the original strand separated from the template. The two semi-conservative molecules formed will have an identical base sequence to the original molecule.

Detailed explanation-2: -Semi-conservative replication. In this model, the two strands of DNA unwind from each other, and each acts as a template for synthesis of a new, complementary strand. This results in two DNA molecules with one original strand and one new strand.

Detailed explanation-3: -Recall that adenine nucleotides pair with thymine nucleotides, and cytosine with guanine. This means that the two strands are complementary to each other. For example, a strand of DNA with a nucleotide sequence of AGTCATGA will have a complementary strand with the sequence TCAGTACT (Figure 9.2. 1).

Detailed explanation-4: -A new DNA strand only grows in the 5’ to 3’ direction because the enzyme that adds new bases to a growing strand requires a free 3’ OH group. The sugar-phosphate backbone of DNA is made up of phosphodiester linkages between 3’ OH groups and 5’ phosphate groups.

Detailed explanation-5: -The result of DNA replication is two DNA molecules consisting of one new and one old chain of nucleotides. This is why DNA replication is described as semi-conservative, half of the chain is part of the original DNA molecule, half is brand new.

There is 1 question to complete.