AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Fill in the complementary sequence that RNA would code off of this DNA sequenceA T C G T T C A T A A G C A T
A
TAG CAA GTA TTCGTA
B
UAG CAA GUA UUCGUA
C
TUG CUU GTU TTCGTU
D
UAG UAA GTA TTUGTA
Explanation: 

Detailed explanation-1: -Two strands of complementary sequence are referred to as sense and anti-sense. The sense strand is, generally, the transcribed sequence of DNA or the RNA that was generated in transcription, while the anti-sense strand is the strand that is complementary to the sense sequence.

Detailed explanation-2: -Expert-Verified Answer The synthesised mRNA will have base sequence complementary to the template strand of the DNA. This complementarity is useful for synthesis of correct sequence of amino acids. Hence, for the given DNA sequence-‘C-A-A-G-G-T’, the correct mRNA sequence will be ‘G-U-U-C-C-A’.

Detailed explanation-3: -An anticodon is a trinucleotide sequence located at one end of a transfer RNA (tRNA) molecule, which is complementary to a corresponding codon in a messenger RNA (mRNA) sequence.

Detailed explanation-4: –According to Chargaff’s base-pairing rules and antiparallel alignment of anticodon and codon, we can say that the tRNA anticodon 3’-UAC-5’ will pair with the mRNA codon 5’-AUG-3’. This codon AUG is the initiation codon and it codes for formyl-Methionine. Thus, the correct answer is C i.e., 5’-AUG-3’.

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