THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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wobble
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gobble
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autonomy
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mismatch
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Detailed explanation-1: -During the pairing between mRNA codons and tRNA anticodons, some tRNAs can form base pairs with more than one codon. This is because atypical base pairing, between nucleotides other than the typical A-U and G-C, can occur at the third position of the codon. This is known as wobble pairing.
Detailed explanation-2: -The wobble position of a codon refers to the 3rd nucleotide in a codon. This nucleotide has two major characteristics: Binding of a codon in an mRNA the cognate tRNA is much “looser” in the third position of the codon. This permits several types of non-Watson–Crick base pairing to occur at the third codon position.
Detailed explanation-3: -Among the most frequent of wobble base pairs are G · T(U) base pairing which arises as a result of keto–enol tautomerism and A · C base pairing which is based on amino–imino tautomerism (Fig. 1.7).