AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How many base pairs are there in one full DNA “twist”?
A
2
B
4
C
8
D
10
Explanation: 

Detailed explanation-1: -The variation of energy with the twist of the base pairs about the helix axis shows the straight DNA free in solution is most stable with about 10 1/2 base pairs per turn rather than 10 as observed in the solid state, whereas superhelical DNA in chromatin is most stable with about 10 base pairs per turn.

Detailed explanation-2: -in chromatin, the structure is most stable with about 10 base pairs per turn. This result explains both the 10-base-pair repeat observed in partial nuclease digests of nucleosomes (8) and also the change in DNA linkage observed when nucleosomes are formed (9, 10).

Detailed explanation-3: -The bases are nearly perpendicular to the helix axis, and adjacent bases are separated by 3.4 . The helical structure repeats every 34, so there are 10 bases (= 34 per repeat/3.4 per base) per turn of helix.

Detailed explanation-4: -The DNA double helix biopolymer of nucleic acid is held together by nucleotides which base pair together. In B-DNA, the most common double helical structure found in nature, the double helix is right-handed with about 10–10.5 base pairs per turn.

Detailed explanation-5: -One turn of Z-DNA has 12 base pairs and the length is 4.56nm. The distance between two adjacent deoxyribonucleotides is 0.37nm. Same as the other forms of DNA, hydrogen bond is present to hold the two strands together. Z-DNA is difficult to be observed since it is unstable.

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