AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
If a strand of DNA had bases in the following order-ATCCGTC, what would be the replicated complementary strand?
A
UAGGCAG
B
ATCCGTC
C
TAGGCAG
D
TUGGCTG
Explanation: 

Detailed explanation-1: -Answer and Explanation: 1. The bases on the other strand would be TAGGCAG. DNA strands are complementary, meaning that A (adenine) and T (thymine) always pair (via 2 hydrogen bonds), and G (guanine) and C (cytosine) always pair (via 3 hydrogen bonds).

Detailed explanation-2: -Complementary Sequence: Since DNA has two strands, every DNA sequence has a complementary sequence running parallel. In the complementary sequence, Adenine (A) is always paired with Thymine (T), and Cytosine (C) is always paired with Guanine (G).

Detailed explanation-3: -Expert-Verified Answer The synthesised mRNA will have base sequence complementary to the template strand of the DNA. This complementarity is useful for synthesis of correct sequence of amino acids. Hence, for the given DNA sequence-‘C-A-A-G-G-T’, the correct mRNA sequence will be ‘G-U-U-C-C-A’.

Detailed explanation-4: -Answer and Explanation: The complementary DNA strand of the sequence ATGC will be TACG. The complementary base pairing in DNA is as per the Chargaff’s rules. According to these rules, purines always hydrogen bond with pyrimidines and vice-versa.

Detailed explanation-5: -However, mRNA does not consist of the same four bases as DNA. While DNA has the ATCG nitrogenous bases, RNA replaces thymine with uracil, making its bases AUCG.

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