AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In a DNA molecule, the bonds between the nitrogenous bases are much weaker than the bonds joining the phosphate groups to the sugars. Why is this significant to the DNA molecule?
A
The strength of the bonds determine the type of DNA produced during the process of replication.
B
This difference in bonding allows the bases to break away from thephosphate-sugar side chains.
C
The bonds between the sugars and phosphate maintain the DNAstrand while the base bonds break during replication.
D
The bonds between the phosphates and the sugars are unbreakable ionic bonds, while the base-to-base bonds are covalent.
Explanation: 

Detailed explanation-1: -Hydrogen bonds occur between the two strands and involve a base from one strand with a base from the second in complementary pairing. These hydrogen bonds are individually weak but collectively quite strong.

Detailed explanation-2: -The sugar-phosphate backbone, as mentioned, is an important component of DNA’s double helix structure. The structure of DNA is tied to its function. The pairing of the nitrogenous bases that are connected to the sugar-phosphate backbone play a key role in the ability of DNA to store and transfer genetic information.

Detailed explanation-3: -Answer and Explanation: The answer is B: hydrogen bonds are easier to break allowing for DNA copying. Hydrogen bonds formed between complementary base pairs on opposite DNA strands form the “rungs on a ladder” portion of DNA’s double-helical structure.

Detailed explanation-4: -Two successive nucleotides of DNA are joined by phosphodiester linkage in which the 5’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide. Thus, phosphate and pentose sugars of DNA are joined by phosphodiester linkage; the correct answer is B.

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