THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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5’ to 3’ direction
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3’ to 5’ direction
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Detailed explanation-1: -All mRNAs are read in the 5´ to 3´ direction, and polypeptide chains are synthesized from the amino to the carboxy terminus. Each amino acid is specified by three bases (a codon) in the mRNA, according to a nearly universal genetic code.
Detailed explanation-2: -Nucleic acids can only be synthesized in vivo in the 5′-to-3′ direction, as the polymerases that assemble various types of new strands generally rely on the energy produced by breaking nucleoside triphosphate bonds to attach new nucleoside monophosphates to the 3′-hydroxyl (−OH) group, via a phosphodiester bond.
Detailed explanation-3: -DNA is always synthesized in the 5’-to-3’ direction, meaning that nucleotides are added only to the 3’ end of the growing strand. As shown in Figure 2, the 5’-phosphate group of the new nucleotide binds to the 3’-OH group of the last nucleotide of the growing strand.
Detailed explanation-4: -5. mRNAs can be modified on the 5’ and 3’ ends.
Detailed explanation-5: -During transcription, the RNA polymerase read the template DNA strand in the 3′