THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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There aren’t different types of point mutations.
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Detailed explanation-1: -Single base substitutions are called point mutations, recall the point mutation Glu—–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.
Detailed explanation-2: -There are two types of point mutations: transition mutations and transversion mutations. Transition mutations occur when a pyrimidine base (i.e., thymine [T] or cytosine [C]) substitutes for another pyrimidine base or when a purine base (i.e., adenine [A] or guanine [G]) substitutes for another purine base.
Detailed explanation-3: -Types of Point Mutations. We are going to focus on the following point mutations: frameshift, silent, nonsense, and missense. Let’s start with a frameshift mutation, where there’s an insertion or deletion of one or more bases.
Detailed explanation-4: -A point mutation is going to change one nucleotide in the DNA code, this may or may not result in a changed amino acid. A missense mutation is always going to be a substitution of one amino acid for another.