THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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5’
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3’
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5’
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3’
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Detailed explanation-1: -DNA is always synthesized in the 5’-to-3’ direction, meaning that nucleotides are added only to the 3’ end of the growing strand. As shown in Figure 2, the 5’-phosphate group of the new nucleotide binds to the 3’-OH group of the last nucleotide of the growing strand.
Detailed explanation-2: -Each end of DNA molecule has a number. One end is referred to as 5’ (five prime) and the other end is referred to as 3’ (three prime). The 5’ and 3’ designations refer to the number of carbon atom in a deoxyribose sugar molecule to which a phosphate group bonds.
Detailed explanation-3: -Any single strand of DNA/RNA will always have an unbound 5’ phosphate at one end and an unbound 3’ hydroxyl group at the opposite end. DNA is always read in the 5’ to 3’ direction, and hence you would start reading from the free phosphate and finish at the free hydroxyl group.
Detailed explanation-4: -The template strand is directed in the 5’ to 3’ direction. The coding strand has a complementary nucleotide sequence. The template strand does not have any complementary sequence.