THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Outside of the Nucleus
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Inside of the Nucleus
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Detailed explanation-1: -In transcription, DNA is converted to mRNA. It takes place in the nucleus of a cell. The newly formed mRNA, undergoes processing, and moves out into the cytoplasm through the nuclear pores, to proceed with the next step of protein synthesis, which is translation.
Detailed explanation-2: -Transcription occurs in the nucleus whereas the major mRNA decay pathways operate in the cytoplasm. As synthesis and decay processes contribute equally to maintaining mRNA levels, it is quite likely that organisms have evolved a mechanism to coordinate events in the two compartments.
Detailed explanation-3: -The eukaryotic nucleus therefore provides a distinct compartment within the cell, allowing transcription and splicing to proceed prior to the beginning of translation. Thus, in eukaryotes, while transcription occurs in the nucleus, translation occurs in the cytoplasm.
Detailed explanation-4: -The most prominent substructure within the nucleus is the nucleolus (see Figure 8.1), which is the site of rRNA transcription and processing, and of ribosome assembly.
Detailed explanation-5: -In eukaryotes, transcription occurs in the nucleus, and translation occurs in the cytoplasm.