THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What enzyme initiates DNA replication?
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DNA polymerase
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tRNA
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RNA polymerase
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mRNA
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Explanation:
Detailed explanation-1: -The central enzyme involved is DNA polymerase, which catalyzes the joining of deoxyribonucleoside 5′-triphosphates (dNTPs) to form the growing DNA chain. However, DNA replication is much more complex than a single enzymatic reaction.
Detailed explanation-2: -DNA polymerase cannot start the replication process without primer as it adds nucleotides. The replication requires a primer, helicase, SSBPs (single-stranded binding proteins) and DNA polymerase to start it.
Detailed explanation-3: -As we shall see, the process of DNA replication is begun by special initiator proteins that bind to double-stranded DNA and pry the two strands apart, breaking the hydrogen bonds between the bases.
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