THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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When bases are inserted in a DNA strand
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When a base is substitute by another
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When bases are deleted in a DNA strand
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Detailed explanation-1: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
Detailed explanation-2: -If one or two bases are deleted the translational frame is altered resulting in a garbled message and nonfunctional product. A deletion of three or more bases leave the reading frame intact. A deletion of one or more codons results in a protein missing one or more amino acids.
Detailed explanation-3: -A point mutation occurs in a genome when a single base pair is added, deleted or changed. While most point mutations are benign, they can also have various functional consequences, including changes in gene expression or alterations in encoded proteins.
Detailed explanation-4: -A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read.
Detailed explanation-5: -Insertion mutations and deletion mutations are the two forms of frameshift mutations that might occur. Both have a similar overall impact, shifting the translational reading frame out of alignment and producing a random amino acid sequence.