THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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frameshift
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substitution
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deletion
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inversion
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Detailed explanation-1: -Missense: A missense variant is a type of substitution in which the nucleotide change results in the replacement of one protein building block (amino acid) with another in the protein made from the gene.
Detailed explanation-2: -Base substitution Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication.
Detailed explanation-3: -Transversion: when a purine is substituted for a pyrimidine or a pyrimidine replaces a purine. Point mutations that occur in DNA sequences encoding proteins are either silent, missense or nonsense.
Detailed explanation-4: -Substitution mutations can be good, bad, or have no effect. They cause three specific types of point mutation: silent, missense, and nonsense mutations. A silent mutation is one where the function of the protein is not changed. A missense mutation codes for the wrong protein.
Detailed explanation-5: -There are two types of point mutations: transition mutations and transversion mutations. Transition mutations occur when a pyrimidine base (i.e., thymine [T] or cytosine [C]) substitutes for another pyrimidine base or when a purine base (i.e., adenine [A] or guanine [G]) substitutes for another purine base.