THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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single nucleotide repeating proteins
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DNA polymerase I
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RNA primase
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single strand binding proteins
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Detailed explanation-1: -The process of DNA replication can be summarized as follows: DNA unwinds at the origin of replication. Helicase opens up the DNA-forming replication forks; these are extended bidirectionally. Single-strand binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA.
Detailed explanation-2: -Helicase unwinds the helix, and single-strand binding proteins prevent the helix from re-forming. Topoisomerase prevents the DNA from getting too tightly coiled ahead of the replication fork.
Detailed explanation-3: -Topoisomerases (red) reduce torsional strain caused by the unwinding of the DNA double helix; DNA helicase (yellow) breaks hydrogen bonds between complementary base-pairs; single-strand binding proteins (SSBs) stabilize the separated strands and prevent them from rejoining.
Detailed explanation-4: -The helicase pushes the two strands so far apart that they have no chance of finding each other. One of the strands is rapidly degraded, preventing the double helix from re-forming. Single-strand binding proteins bind the unwound DNA and prevent the double helix from re-forming.
Detailed explanation-5: -Single strand binding protein (ssb protein) binds to separated strands of DNA and prevents reannealing.